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Adipose tissue is split into two main types of connective tissue, white and brown, that store and burn energy respectively. White adipose tissue also provides a layer of insulation, while brown adipose tissue is found in quantities in children and adults that are too small to provide insulation. Brown adipose tissue, however, is the one that releases energy in the form of heat. Adipose tissue is made up of adipocytes, cells that play a vital role in the storage and release of energy throughout the body. Fat cells also have an endocrine function as they are able to produce certain hormones in response to signals from the rest of the organs in the body, and through the actions of those hormones. The adipose tissue plays an important role in the regulation of glucose, cholesterol and the metabolism of sex hormones. These include angiogenesis (the production of blood vessels) and blood coagulation, reproduction, glucose metabolism, fat metabolism, and the regulation of appetite and immunity.